Childhood emotional trauma and cyberbullying perpetration among emerging adults: a multiple mediation model of the role of problematic social media use and psychopathology

Research suggests that a small minority of social media users experience problems as a result of their online use. The purpose of the present study was to examine the association of cyberbullying perpetration and problematic social media use with childhood emotional trauma, Cluster B (narcissistic, histrionic, antisocial, and borderline) personality traits, dissociative experiences (DEs), depression, and self-esteem in a nonclinical undergraduate sample. A total of 344 university students volunteered to complete a questionnaire that included measures on the aforementioned dimensions. Thirty-eight percent of the participants had emotional neglect and 27% had emotional abuse, while 44% of them demonstrated at least one cyberbullying perpetration behavior. Results indicated that cyberbullying perpetrators had higher scores on problematic social media use, dissociative experiences, Cluster B traits, depression and childhood emotional trauma, and lower on self-esteem. Path analysis demonstrated that, while adjusting for gender and age, childhood emotional trauma was directly and indirectly associated with cyberbullying perpetration via Cluster B traits. Moreover, depression and dissociation were directly associated with problematic social media use. The findings of this study emphasize the important direct role of childhood emotional trauma and pathological personality traits on cyberbullying perpetration

Successful delivery in a patient with isolated supravalvular aortic stenosis

PMID = 2791916

Investigation of some physical and chemical properties with respect to processing of kaolin samples from Sivas deposits in Turkey

New kaolin deposits were discovered at two different locations in Sivas, Turkey. The first deposit was located in the north of a town called Zara, towards the east of another one called Kosedag. The second deposit was in the north of Susehri, on a mountain called Igdirdag. hi this study, some physical and chemical properties of kaolin samples from those deposits were investigated after illustrating necessary geological information about the area. Mineral processing studies were also carried out to determine the suitable separation method and the related processing parameters, i.e. hydrocycloning for these two different types of kaolins

Evaluation of the level of thiol-disulphide homeostasis in patients with mild and severe preeclampsia

PMID = 2793948

The effect of ink dilution and evaporation on the microstructures of catalyst layers in polymer electrolyte membrane fuel cells

The microstructures of catalyst layers (CLs) in proton exchange membrane fuel cells determine cell performance and durability. Delicate ink preparation processes and coating/drying processes affect the resulting microstructures including active sites, pore networks, ionomer networks and Pt/C networks. This paper reports our recent experimental observations of the effect of ink dilution and evaporation condition on the microstructures. The microstructures of dried ink droplets are presented and compared among different dilution ratios and different evaporation conditions in terms of the spatial distributions of Pt/C particles, ionomers, and pores. The method through which the microstructures are visualized is also introduced in this paper. It is observed that ink dilution ratio and evaporation condition can significantly alter resulting microstructure patterns through affecting viscosity and particle flow patterns during the evaporation. More concentrated solution makes catalyst inks less spread out on a substrate surface, leading to larger droplet height and larger contact angle. Ambient relative humidity has a significant impact on catalyst deposition patterns. Under low relative humidity condition, catalyst particles are concentrated both near the central and the periphery of the droplet; while under high relative humidity, the central part is uniform, and the particles move towards the edge of the deposition, forming a stripe-like structure. This indicates that ink dilution and evaporation is key to the CL microstructure formation and must be properly controlled in order to obtain the quality and consistency of the CLs in fabrication

Generation and Purification of Catalytically Active Recombinant Sirtuin5 (SIRT5) Protein

Sirtuin-family deacylases promote health and longevity in mammals. The sirtuin SIRT5 localizes predominantly to the mitochondrial matrix. SIRT5 preferentially removes negatively charged modifications from its target lysines: succinylation, malonylation, and glutarylation. It regulates protein substrates involved in glucose oxidation, ketone body formation, ammonia detoxification, fatty acid oxidation, and ROS management. Like other sirtuins, SIRT5 has recently been linked with neoplasia. Therefore, targeting SIRT5 pharmacologically could conceivably provide new avenues for treatment of metabolic disease and cancer, necessitating development of SIRT5-selective modulators. Here we describe the generation of SIRT5 bacterial expression plasmids, and their use to express and purify catalytically active and inactive forms of SIRT5 protein from E. coli. Additionally, we describe an approach to assay the catalytic activity of purified SIRT5, potentially useful for identification and validation of SIRT5-specific modulators